Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | PREP | P48147 | 2/20 | 0.53 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.48 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706598 | 0.93 | ACE (0.53) | ACEPREPPSMB9CTRB1CALCRL | |
| SCHEMBL27809460 | 0.92 | ACE (0.57) | ACEPREPPSMB9CTRB1CALCRL | |
| SCHEMBL8257806 | 0.91 | ACE (0.53) | ACEPREPPSMB9CTRB1CALCRL | |
| Carbon Dioxide SCHEMBL2247895 | 0.90 | PREP (0.55) | ACEPREPPSMB9CTRB1CALCRL | |
| SCHEMBL2249471 | 0.90 | ACE (0.55) | ACEPREPPSMB9CTRB1CALCRL | |
| SCHEMBL2249479 | 0.90 | ACE (0.55) | ACEPREPPSMB9CTRB1CALCRL | |
| SCHEMBL2251300 | 0.87 | ACE (0.54) | ACEPREPPSMB9CTRB1CMA1 | |
| SCHEMBL8257798 | 0.87 | ACE (0.54) | ACEPREPPSMB9CTRB1CMA1 | |
| SCHEMBL2249474 | 0.87 | ACE (0.54) | ACEPREPPSMB9CTRB1CMA1 | |
| SCHEMBL8259054 | 0.87 | ACE (0.54) | ACEPREPPSMB9CTRB1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589066-B2 | Such as N-carbobenzyloxy-phenylalanyl-phenylalanylal; for treating cancer, inflammation, and/or autoimmune diseases; suppresses endogenous antigenic peptide generation | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-09-15 | — | — | US | disclosed |