SCHEMBL13707384

SCHEMBL13707384

COC(=O)CNC(=O)C(C)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.48
RECQL P46063 1/20 0.47
BIRC2 Q13490 1/20 0.41
TSHR P16473 6/20 0.41
HSD17B10 Q99714 3/20 0.39
GAA P10253 2/20 0.38
KDM4E B2RXH2 2/20 0.38
EPHX2 P34913 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
PTGS2 P35354 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ECE1 P42892 1/20 0.37
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17037457 1.00 TET2 (0.48) TET2RECQLBIRC2TSHRHSD17B10
SCHEMBL13295878 0.82 TET2 (0.52) TET2RECQLBIRC2TSHRHSD17B10
SCHEMBL29037228 0.80 MEN1 (0.50) TET2RECQLBIRC2TSHRHSD17B10
SCHEMBL19319010 0.79 TET2 (0.45) TET2RECQLBIRC2TSHRHSD17B10
SCHEMBL16668048 0.79 TET2 (0.45) TET2RECQLBIRC2TSHRHSD17B10
SCHEMBL9805212 0.79 TET2 (0.45) TET2RECQLBIRC2TSHRHSD17B10
SCHEMBL38660142 0.78 MAPT (0.63) TET2RECQLBIRC2TSHRHSD17B10
SCHEMBL5641925 0.78 TET2 (0.48) TET2RECQLBIRC2TSHRHSD17B10
SCHEMBL6468610 0.78 MAPT (0.63) TET2RECQLBIRC2TSHRHSD17B10
SCHEMBL16000761 0.78 TET2 (0.48) TET2RECQLBIRC2TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090233221-A1 NEGATIVE-WORKING PHOTOSENSITIVE MATERIAL AND NEGATIVE-WORKING PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed