⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13708283 | 1.00 | — | — | |
| SCHEMBL15177113 | 0.89 | — | — | |
| SCHEMBL13708251 | 0.89 | — | — | |
| SCHEMBL13708253 | 0.89 | — | — | |
| SCHEMBL12362218 | 0.88 | — | — | |
| SCHEMBL13708265 | 0.88 | — | — | |
| SCHEMBL12362224 | 0.87 | — | — | |
| SCHEMBL13708264 | 0.87 | — | — | |
| SCHEMBL13708286 | 0.86 | — | — | |
| SCHEMBL13708254 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8506932-B2 | Tetracyclic indole derivatives as in vivo imaging agents and having peripheralbenzodiazepine receptor affinity (PBR) | HAMMERSMITH IMANET LIMITED (GB) | 2013-08-13 | — | — | US | disclosed |
| US-8506932-B2 | Tetracyclic indole derivatives as in vivo imaging agents and having peripheralbenzodiazepine receptor affinity (PBR) | HAMMERSMITH IMANET LIMITED (GB) | 2013-08-13 | — | — | US | disclosed |
| US-20090220420-A1 | TETRACYCLIC INDOLE DERIVATIVES AS IN VIVO IMAGING AGENTS AND HAVING PERIPHERALBENZODIAZEPINE RECEPTOR AFFINITY (PBR) | GE HEALTHCARE LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |