Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.48 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.45 |
| ▸ | NOS2 | P35228 | 6/20 | 0.43 |
| ▸ | NOS3 | P29474 | 5/20 | 0.43 |
| ▸ | NOS1 | P29475 | 5/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 4/20 | 0.38 |
| ▸ | ARG1 | P05089 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL1460394 | 1.00 | OTC (0.48) | OTCDDAH1NOS2NOS3NOS1 | |
| Arginine SCHEMBL28873871 | 0.98 | OTC (0.47) | OTCDDAH1NOS2NOS3NOS1 | |
| Arginine SCHEMBL28311538 | 0.97 | OTC (0.46) | OTCDDAH1NOS2NOS3NOS1 | |
| Arginine SCHEMBL28677386 | 0.94 | OTC (0.43) | OTCDDAH1NOS2NOS3NOS1 | |
| Arginine SCHEMBL27731534 | 0.93 | OTC (0.49) | OTCDDAH1NOS2NOS3NOS1 | |
| Arginine SCHEMBL15323931 | 0.92 | OTC (0.42) | OTCDDAH1NOS2NOS3NOS1 | |
| Arginine SCHEMBL15323048 | 0.91 | OTC (0.41) | OTCDDAH1NOS2NOS3NOS1 | |
| Arginine SCHEMBL2899152 | 0.90 | OTC (0.50) | OTCDDAH1NOS2NOS3NOS1 | |
| Arginine SCHEMBL344773 | 0.90 | OTC (0.50) | OTCDDAH1NOS2NOS3NOS1 | |
| Arginine SCHEMBL27841789 | 0.90 | OTC (0.50) | OTCDDAH1NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019175632-A1 | METHODS FOR REFOLDING ISOMALTULOSE SYNTHASE | PETIVA PRIVATE LIMITED (IN) | 2019-09-19 | — | — | WO | claimed |
| CN-109010122-A | A kind of Soap-base facial cleanser and preparation method thereof | 湖南御家化妆品制造有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-108836884-A | A kind of Soap-base facial cleanser and preparation method thereof | 湖南御家化妆品制造有限公司 | 2018-11-20 | — | — | CN | claimed |
| CN-108753617-A | A kind of purification process of arginine strain | 广东肇庆星湖生物科技股份有限公司 | 2018-11-06 | — | — | CN | claimed |
| US-20240238429-A1 | DELIVERY CONSTRUCTS FOR TRANSCYTOSIS AND RELATED METHODS | APPLIED MOLECULAR TRANSPORT INC. | 2024-07-18 | — | — | US | disclosed |
| CN-116712940-A | Plasma modified amino acid group eutectic solvent microcapsule and preparation method and application thereof | 中国药科大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-112877261-B | Fermentation method of biocontrol streptomyces | 吉林省林业科学研究院 | 2023-06-16 | — | — | CN | disclosed |
| EP-3453694-B1 | BIO-FERTILISER FOR INCREASING CROP YIELDS | CENTRO DE INVESTIG Y ASISTENCIA EN TECNOLOGIA Y DISENO DEL ESTADO DE JALISCO A C CIATEJ A C (MX) | 2023-05-31 | — | — | EP | disclosed |
| CN-115252533-A | Moisturizing and repairing composition and preparation method and application thereof | 广州瑞誉化工科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-113061551-B | Application of biocontrol streptomyces in preventing and treating plant disease pathogenic bacteria | 吉林省林业科学研究院 | 2022-05-27 | — | — | CN | disclosed |
| CN-113025537-B | Fermentation method of streptomycete | 吉林省林业科学研究院 | 2022-02-01 | — | — | CN | disclosed |
| US-20210338828-A1 | DELIVERY CONSTRUCTS FOR TRANSCYTOSIS AND RELATED METHODS | THORNHILL THERAPEUTICS, INC. | 2021-11-04 | — | — | US | disclosed |
| US-20130137131-A1 | System and Method of Producing Volatile Organic Compounds from Fungi | STROBEL GARY A (US) | 2013-05-30 | — | — | US | disclosed |
| EP-2571995-A1 | SYSTEM AND METHOD OF PRODUCING VOLATILE ORGANIC COMPOUNDS FROM FUNGI | Strobel, Gary A. (US) | 2013-03-27 | — | — | EP | disclosed |
| CN-102876622-A | Biocontrol bacterium and application of biocontrol bacterium to preventing and controlling cotton blight and cotton greensickness | UNIV TARIM | 2013-01-16 | — | — | CN | disclosed |
| WO-2012166810-A1 | BIOLOGICALLY ACTIVE TRI-PEPTIDE | AMPLIFI BIOTECHNOLOGIES, INC. (US) | 2012-12-06 | — | — | WO | disclosed |
| WO-2011146634-A1 | SYSTEM AND METHOD OF PRODUCING VOLATILE ORGANIC COMPOUNDS FROM FUNGI | STROBEL GARY A (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110287471-A1 | System and Method of Producing Volatile Organic Compounds from Fungi | STROBEL GARY A (US) | 2011-11-24 | — | — | US | disclosed |
| WO-2011025395-A1 | ANTI-PHYTOPATHOGENIC COMPOSITIONS | CROP SOLUTIONS 2009 LIMITED (NZ) | 2011-03-03 | — | — | WO | disclosed |
| US-4104369-A | ANTINEOPLASTIC ACTIVITY | STATE OF MICHIGAN (US) | 1978-08-01 | — | — | US | disclosed |