Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10314502 | 0.91 | HDAC1 (0.44) | DRD4RXFP1 | |
| Hydrochloric Acid SCHEMBL1061359 | 0.91 | HDAC1 (0.43) | DRD4RXFP1 | |
| SCHEMBL1083650 | 0.88 | F10 (0.47) | F10DRD4RXFP1TP53 | |
| SCHEMBL1060724 | 0.83 | SMO (0.45) | — | |
| SCHEMBL17667836 | 0.82 | F10 (0.41) | F10DRD4TP53 | |
| SCHEMBL1057353 | 0.82 | SMO (0.47) | F10DRD4TP53 | |
| SCHEMBL1062334 | 0.80 | SMO (0.42) | F10DRD4TP53 | |
| SCHEMBL1061924 | 0.80 | DRD4 (0.49) | DRD4TP53 | |
| SCHEMBL1063452 | 0.78 | SMO (0.43) | — | |
| SCHEMBL1062906 | 0.78 | DRD4 (0.43) | DRD4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009107850-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-03 | — | — | WO | disclosed |