Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 18/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.49 |
| ▸ | TCF7 | P36402 | 2/20 | 0.49 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | TCF4 | P15884 | 1/20 | 0.49 |
| ▸ | CLPP | Q16740 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749978 | 0.94 | CYP3A4 (0.51) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL748668 | 0.89 | CYP3A4 (0.51) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL747957 | 0.86 | CTNNB1 (0.57) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL10224821 | 0.85 | CTNNB1 (0.55) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL749521 | 0.85 | CTNNB1 (0.55) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL746324 | 0.85 | CTNNB1 (0.55) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL747952 | 0.85 | CYP3A4 (0.53) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL749339 | 0.85 | CTNNB1 (0.55) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL747734 | 0.85 | CTNNB1 (0.55) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL748842 | 0.85 | CYP3A4 (0.52) | CYP3A4CTNNB1TCF7BCL9TCF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585862-B2 | Colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss | CHOONGWAE PHARMA CORPORATION (KR) | 2009-09-08 | — | — | US | disclosed |