Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13710463 | 0.88 | SCN9A (0.65) | SCN9ASCN10A | |
| SCHEMBL4505072 | 0.81 | SCN9A (1.00) | SCN9ASCN10A | |
| SCHEMBL4489012 | 0.80 | SCN9A (0.67) | SCN9ASCN10A | |
| SCHEMBL4491451 | 0.79 | SCN9A (0.70) | SCN9ASCN10A | |
| SCHEMBL13710537 | 0.78 | SCN9A (1.00) | SCN9ASCN10A | |
| SCHEMBL13710529 | 0.78 | SCN9A (1.00) | SCN9ASCN10A | |
| SCHEMBL4498206 | 0.77 | SCN9A (0.70) | SCN9ASCN10A | |
| SCHEMBL13710363 | 0.77 | SCN9A (0.74) | SCN9ASCN10A | |
| SCHEMBL13710452 | 0.76 | SCN9A (0.84) | SCN9ASCN10A | |
| SCHEMBL13710733 | 0.76 | SCN9A (0.83) | SCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589116-B2 | Biaryl substituted pyrazoles as sodium channel blockers | MERCK & CO. INC. (US) | 2009-09-15 | — | — | US | disclosed |
| US-7589116-B2 | Biaryl substituted pyrazoles as sodium channel blockers | MERCK & CO. INC. (US) | 2009-09-15 | — | — | US | disclosed |