Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11984042 | 0.85 | CYP3A4 (0.37) | — | |
| SCHEMBL12349946 | 0.85 | ADRB3 (0.33) | — | |
| SCHEMBL12844500 | 0.84 | ADRB3 (0.34) | DPP8DPP9DPP7 | |
| SCHEMBL7868212 | 0.84 | ADRB3 (0.34) | DPP8DPP9DPP7 | |
| SCHEMBL8238244 | 0.82 | — | — | |
| SCHEMBL7868816 | 0.81 | ADRB3 (0.37) | — | |
| SCHEMBL7877261 | 0.81 | ADRB3 (0.36) | — | |
| SCHEMBL8247208 | 0.81 | ADRB3 (0.31) | — | |
| SCHEMBL13711270 | 0.80 | — | — | |
| SCHEMBL497884 | 0.80 | ADRB3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103623-A2 | Novel macrocyclic inhibitors of Hepatitis C virus replication | Intermune, Inc. (US) | 2009-09-23 | — | — | EP | disclosed |