Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 18/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.53 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.53 |
| ▸ | ITGB6 | P18564 | 5/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13712253 | 0.93 | ITGAV (0.52) | ITGAVITGB3ITGB5ITGB6ITGA5 | |
| SCHEMBL275460 | 0.92 | ITGAV (0.52) | ITGAVITGB3ITGB5ITGB6ITGA5 | |
| SCHEMBL2411157 | 0.92 | ITGAV (0.57) | ITGAVITGB3ITGB5ITGB6ITGA5 | |
| SCHEMBL275631 | 0.85 | ITGAV (0.47) | ITGAVITGB3ITGB5ITGB6ITGA5 | |
| SCHEMBL8350656 | 0.85 | ITGAV (0.47) | ITGAVITGB3ITGB5ITGB6ITGA5 | |
| SCHEMBL2411809 | 0.85 | ITGAV (0.51) | ITGAVITGB3ITGB5ITGB6ITGA5 | |
| SCHEMBL2951966 | 0.84 | ITGAV (0.52) | ITGAVITGB3ITGB5ITGB6ITGA5 | |
| SCHEMBL2951965 | 0.84 | ITGAV (0.52) | ITGAVITGB3ITGB5ITGB6ITGA5 | |
| SCHEMBL277546 | 0.82 | ITGAV (0.62) | ITGAVITGB3ITGB5ITGB6ITGA5 | |
| SCHEMBL5584350 | 0.82 | ITGAV (0.62) | ITGAVITGB3ITGB5ITGB6ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582640-B2 | Vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same | GALAPAGOS SAS (FR) | 2009-09-01 | — | — | US | disclosed |