Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.50 |
| ▸ | ITGB6 | P18564 | 15/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.50 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2450787 | 0.91 | ITGAV (0.60) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL328186 | 0.91 | ITGAV (0.60) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL327985 | 0.90 | ITGAV (0.52) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL8268188 | 0.90 | ITGAV (0.52) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL328067 | 0.89 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL13237288 | 0.89 | ITGAV (0.64) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL5585150 | 0.87 | ITGAV (0.50) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL10202486 | 0.87 | ITGAV (0.50) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL327990 | 0.86 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL328082 | 0.85 | ITGAV (0.60) | ITGAVITGB6ITGB3ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582640-B2 | Vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same | GALAPAGOS SAS (FR) | 2009-09-01 | — | — | US | disclosed |