Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367705 | 1.00 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL13712602 | 1.00 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL10456223 | 0.92 | ADORA2A (0.58) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL1244350 | 0.92 | ADORA2A (0.58) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL1244347 | 0.92 | ADORA2A (0.58) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL14393651 | 0.92 | ADORA2A (0.58) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL1245456 | 0.90 | ADORA2A (0.62) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL10456065 | 0.90 | ADORA2A (0.62) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL1245453 | 0.90 | ADORA2A (0.62) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL14393414 | 0.90 | ADORA2A (0.62) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589076-B2 | Substituted aryl piperidinylalkynyladenosines as A2AR agonists | PGX HEALTH, LLC (US) | 2009-09-15 | — | — | US | disclosed |