Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.61 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | CALCA | P06881 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13331841 | 1.00 | CALCRL (0.61) | CALCRLRAMP1CYP3A4CALCA | |
| SCHEMBL13713220 | 0.96 | CALCRL (0.60) | CALCRLRAMP1CYP3A4CALCA | |
| SCHEMBL13331844 | 0.96 | CALCRL (0.60) | CALCRLRAMP1CYP3A4CALCA | |
| SCHEMBL13331816 | 0.96 | CALCRL (0.64) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13713217 | 0.96 | CALCRL (0.64) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13331846 | 0.95 | CALCRL (0.62) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13713291 | 0.95 | CALCRL (0.62) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13713289 | 0.94 | CALCRL (0.62) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13331832 | 0.94 | CALCRL (0.62) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL2165156 | 0.94 | CALCRL (0.66) | CALCRLRAMP1CYP3A4CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595312-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2009-09-29 | — | — | US | disclosed |