Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736744 | 0.80 | CNR2 (0.52) | CNR2CNR1 | |
| SCHEMBL2736748 | 0.77 | CNR2 (0.50) | CNR2CNR1 | |
| SCHEMBL2736750 | 0.76 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL2736749 | 0.73 | CNR2 (0.58) | CNR2CNR1ALDH1A1 | |
| SCHEMBL2736747 | 0.72 | CNR2 (0.62) | CNR2CNR1ALDH1A1 | |
| SCHEMBL14865377 | 0.66 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL14099779 | 0.66 | TSHR (0.53) | CNR2CNR1KMT2AALDH1A1TSHR | |
| SCHEMBL5573848 | 0.65 | CNR2 (0.65) | CNR2CNR1ALDH1A1 | |
| SCHEMBL5524492 | 0.65 | CNR2 (0.65) | CNR2CNR1ALDH1A1 | |
| Decane SCHEMBL28986149 | 0.65 | MTOR (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357111-B1 | 2-PYRIDONE DERIVATIVES HAVING AFFINITY FOR CANNABINOID TYPE 2 RECEPTOR | SHIONOGI & CO (JP) | 2009-08-05 | — | — | EP | disclosed |