Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.67 |
| ▸ | CNR1 | P21554 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5538681 | 0.87 | CNR2 (0.55) | CNR2CNR1HTTSMN1; SMN2MEN1 | |
| SCHEMBL216656 | 0.84 | CNR2 (0.66) | CNR2CNR1NPC1LMNARAB9A | |
| SCHEMBL2736528 | 0.84 | CNR2 (0.66) | CNR2CNR1NPC1LMNARAB9A | |
| SCHEMBL13716013 | 0.83 | CNR2 (0.62) | CNR2CNR1NPC1LMNARAB9A | |
| SCHEMBL216352 | 0.82 | CNR2 (0.79) | CNR2CNR1 | |
| SCHEMBL217768 | 0.81 | CNR2 (0.60) | CNR2CNR1NPC1LMNARAB9A | |
| SCHEMBL217087 | 0.81 | CNR2 (0.63) | CNR2CNR1NPC1PDE1APDE1B | |
| SCHEMBL217884 | 0.81 | CNR2 (0.77) | CNR2CNR1 | |
| SCHEMBL3177343 | 0.81 | CNR2 (1.00) | CNR2CNR1NPC1 | |
| SCHEMBL14215468 | 0.81 | CNR2 (0.47) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357111-B1 | 2-PYRIDONE DERIVATIVES HAVING AFFINITY FOR CANNABINOID TYPE 2 RECEPTOR | SHIONOGI & CO (JP) | 2009-08-05 | — | — | EP | disclosed |