Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.63 |
| ▸ | PTPRA | P18433 | 2/20 | 0.63 |
| ▸ | PTPRF | P10586 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 2/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157766 | 0.87 | MAPT (0.67) | PTPN1PTPRAPTPRFMAPTMEN1 | |
| SCHEMBL12839858 | 0.81 | MAPT (0.78) | PTPN1PTPRAPTPRFMAPTMEN1 | |
| SCHEMBL3076668 | 0.80 | PTPN1 (0.75) | PTPN1PTPRAPTPRFMAPTKMT2A | |
| SCHEMBL2157462 | 0.79 | PTPN1 (0.62) | PTPN1PTPRAPTPRFMAPTMEN1 | |
| SCHEMBL2252377 | 0.79 | PTPN1 (0.55) | PTPN1PTPRAPTPRFMAPTMEN1 | |
| SCHEMBL6311435 | 0.78 | PTPN1 (1.00) | PTPN1PTPRAPTPRFKMT2AKDM4E | |
| SCHEMBL6534391 | 0.78 | PTPN1 (0.75) | PTPN1PTPRAPTPRFMAPTPOLB | |
| SCHEMBL3064014 | 0.77 | IKBKB (0.83) | PTPN1PTPRAPTPRFMAPTMEN1 | |
| SCHEMBL3070348 | 0.77 | IKBKB (0.82) | PTPN1PTPRAPTPRFMAPTMEN1 | |
| SCHEMBL2157661 | 0.76 | HPGD (0.84) | MAPTPOLBKMT2ATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | disclosed |