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Sugi Predict / Compounds / SCHEMBL13716183

SCHEMBL13716183

SCHEMBL13716183

Nc1nc2c(ncn2[C@H]2CC3OP(=O)(O)OC[C@H]4O[C@@H](n5cnc6c(=O)[nH]c(N)nc65)CC4OP(=O)(O)OCC[C@H]3O2)c(=O)[nH]1

nearest known ligand 0.89

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 17/20 0.70
▸ PDE3B Q13370 1/20 0.63
▸ PDE3A Q14432 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29885238 0.94 STING1 (0.77) STING1PDE3BPDE3A
SCHEMBL23477127 0.94 STING1 (0.77) STING1PDE3BPDE3A
SCHEMBL13341136 0.94 STING1 (0.77) STING1PDE3BPDE3A
SCHEMBL9926172 0.94 STING1 (0.77) STING1PDE3BPDE3A
SCHEMBL13341164 0.94 STING1 (0.77) STING1PDE3BPDE3A
SCHEMBL13716186 0.91 STING1 (0.80) STING1PDE3BPDE3A
SCHEMBL20321040 0.89 STING1 (0.72) STING1
SCHEMBL22434632 0.88 STING1 (0.87) STING1
SCHEMBL13367629 0.85 STING1 (0.87) STING1PDE3BPDE3A
SCHEMBL23476871 0.85 STING1 (0.87) STING1PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569555-B2 Method for stimulating the immune, inflammatory or neuroprotective response KARAGEN PHARMACEUTICALS 2009-08-04 — — US disclosed
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