Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282937 | 1.00 | NR1I2 (0.34) | NR1I2LMNAPGR | |
| SCHEMBL19215821 | 0.85 | PAOX (0.39) | NR1I2LMNAPGR | |
| SCHEMBL17448382 | 0.83 | — | — | |
| SCHEMBL12707557 | 0.81 | — | — | |
| SCHEMBL1270041 | 0.79 | SQLE (0.35) | NR1I2LMNAPGR | |
| SCHEMBL14160212 | 0.79 | SQLE (0.35) | NR1I2LMNAPGR | |
| SCHEMBL20707220 | 0.77 | NR1I2 (0.35) | NR1I2LMNAPGR | |
| SCHEMBL13066581 | 0.77 | NR1I2 (0.32) | NR1I2LMNAPGR | |
| SCHEMBL23073894 | 0.76 | — | — | |
| SCHEMBL17448381 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1249233-B9 | NPYY5 ANTAGONISTS | SHIONOGI & CO (JP) | 2009-08-05 | — | — | EP | disclosed |
| EP-1249233-B1 | NPYY5 ANTAGONISTS | SHIONOGI & CO (JP) | 2008-08-20 | — | — | EP | disclosed |