SCHEMBL1371688

SCHEMBL1371688

CC(C)C[C@H](NC(=O)CN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ GNPAT O15228 2/20 0.50
▸ SLC15A2 Q16348 1/20 0.50
▸ FOLH1 Q04609 5/20 0.49
▸ CPB2 Q96IY4 6/20 0.45
▸ ERAP2 Q6P179 1/20 0.44
▸ ERAP1 Q9NZ08 1/20 0.44
▸ LNPEP Q9UIQ6 1/20 0.44
▸ GRIN2D O15399 1/20 0.43
▸ GRIN3B O60391 1/20 0.43
▸ GRIN1 Q05586 1/20 0.43
▸ GRIN2A Q12879 1/20 0.43
▸ GRIN2B Q13224 1/20 0.43
▸ GRIN2C Q14957 1/20 0.43
▸ GRIN3A Q8TCU5 1/20 0.43
▸ NMT2 O60551 1/20 0.43
▸ NMT1 P30419 1/20 0.43
▸ SLC6A5 Q9Y345 1/20 0.43
▸ MME P08473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28809596 1.00 GNPAT (0.50) GNPATSLC15A2FOLH1CPB2ERAP2
SCHEMBL30394925 0.94 SLC15A2 (0.55) SLC15A2FOLH1CPB2ERAP2ERAP1
SCHEMBL29904373 0.94 SLC15A2 (0.55) SLC15A2FOLH1CPB2ERAP2ERAP1
SCHEMBL30974511 0.92 FOLH1 (0.52) GNPATSLC15A2FOLH1CPB2GRIN2D
SCHEMBL30312568 0.91 FOLH1 (0.57) GNPATSLC15A2FOLH1CPB2NMT2
SCHEMBL30918795 0.90 SLC15A2 (0.43) GNPATSLC15A2FOLH1CPB2ERAP2
SCHEMBL30636768 0.89 GNPAT (0.51) GNPATSLC15A2FOLH1CPB2ERAP2
SCHEMBL30391698 0.87 MME (0.50) GNPATFOLH1MME
SCHEMBL30296770 0.86 NMT1 (0.53) SLC15A2FOLH1CPB2GRIN2DGRIN3B
SCHEMBL34473976 0.86 SLC15A2 (0.54) GNPATSLC15A2FOLH1CPB2NMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111187760-B Enzyme with acyl transfer function and application thereof 中国海洋大学 2022-09-13 — — CN disclosed
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC (CA) 2016-09-15 — — US disclosed
EP-2794663-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF Angiochem Inc. (CA) 2014-10-29 — — EP disclosed
CN-103665170-A Peptide therapeutic conjugates and uses thereof ANGIOCHEM INC 2014-03-26 — — CN disclosed
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2011-11-24 — — US disclosed
WO-2010063124-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2010-06-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 GNPAT 2672/4885SLC15A2 83/4885FOLH1 144/4885
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 GNPAT 2672/4885SLC15A2 83/4885FOLH1 144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback