Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31588497 | 1.00 | TSHR (0.39) | TSHRSMPD1FDPSLMNADNM1 | |
| SCHEMBL3449828 | 0.81 | TSHR (0.38) | TSHRFDPSLMNADNM1ADH1B | |
| SCHEMBL964642 | 0.80 | TSHR (0.34) | TSHRSMPD1LMNADNM1ADH1B | |
| SCHEMBL959295 | 0.80 | TSHR (0.34) | TSHRSMPD1LMNADNM1ADH1B | |
| SCHEMBL1398288 | 0.79 | TSHR (0.33) | TSHRSMPD1LMNADNM1ADH1B | |
| SCHEMBL1398299 | 0.79 | TSHR (0.33) | TSHRSMPD1LMNADNM1ADH1B | |
| SCHEMBL963368 | 0.78 | TSHR (0.35) | TSHRSMPD1LMNADNM1ADH1B | |
| SCHEMBL29243946 | 0.78 | TSHR (0.35) | TSHRSMPD1LMNADNM1ADH1B | |
| SCHEMBL961781 | 0.78 | TSHR (0.35) | TSHRSMPD1LMNADNM1ADH1B | |
| SCHEMBL28886159 | 0.78 | TSHR (0.35) | TSHRSMPD1LMNADNM1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572928-B2 | Fluorination process | ISIS INNOVATION LIMITED (GB) | 2009-08-11 | — | — | US | disclosed |
| US-20070142632-A1 | Fluorination process | ISIS INNOVATION LIMITED (GB) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142632-A1 | Fluorination process | CYP2F1, SF3A2, SF3B2 | TSHR 2174/4885SMPD1 844/4885FDPS 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.