Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13747046 | 0.88 | GAA (0.46) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL28462516 | 0.82 | TSHR (0.57) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL7642945 | 0.81 | TSHR (0.73) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL1138704 | 0.80 | TSHR (0.71) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL22654966 | 0.79 | GAA (0.70) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL9314891 | 0.79 | TSHR (0.54) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL14365439 | 0.78 | TSHR (0.68) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL1939153 | 0.77 | KMT2A (0.71) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL20995314 | 0.77 | GAA (0.68) | GAATSHRKMT2AMEN1SCN1A | |
| SCHEMBL1138523 | 0.76 | TSHR (0.65) | GAATSHRKMT2AMEN1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579411-B2 | Process for the controlled increase in the molecular weight of polyethylenes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-08-25 | — | — | US | disclosed |
| US-20080146740-A1 | Process for the controlled increase in the molecular weight of polyethylenes | ROTH MICHAEL | 2008-06-19 | — | — | US | disclosed |