Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13721697 | 0.91 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL728650 | 0.90 | TLR7 (0.61) | TLR7TLR8 | |
| SCHEMBL3815273 | 0.90 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL3814801 | 0.90 | TLR7 (0.69) | TLR7TLR8 | |
| Hydrochloric Acid SCHEMBL3814308 | 0.89 | TLR7 (0.62) | TLR7TLR8 | |
| SCHEMBL3972922 | 0.89 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL3971954 | 0.87 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL3973006 | 0.87 | TLR7 (0.67) | TLR7TLR8 | |
| SCHEMBL13721862 | 0.87 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL14516468 | 0.86 | TLR7 (0.63) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642580-B1 | Sulfonamide substituted imidazoquinolines | COLEY PHARM GROUP INC (US) | 2009-08-19 | — | — | EP | disclosed |
| US-7199131-B2 | Sulfonamide and sulfamide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-04-03 | — | — | US | disclosed |
| US-7199131-B2 | Sulfonamide and sulfamide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-04-03 | — | — | US | disclosed |