Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 16/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13721939 | 0.92 | GSK3B (0.57) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13721496 | 0.90 | GSK3B (0.55) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13721482 | 0.90 | GSK3B (0.55) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13722071 | 0.90 | GSK3B (0.55) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13721969 | 0.90 | GSK3B (0.52) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13722021 | 0.89 | GSK3B (0.57) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13722029 | 0.89 | GSK3B (0.57) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13722299 | 0.89 | GSK3B (0.49) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13722002 | 0.88 | GSK3B (0.49) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13721621 | 0.88 | GSK3B (0.53) | GSK3BCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |