Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.80 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.80 |
| ▸ | GSK3A | P49840 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497011 | 0.93 | GSK3B (0.72) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL497265 | 0.92 | GSK3B (0.71) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13722726 | 0.91 | GSK3B (0.86) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13723010 | 0.90 | GSK3B (0.76) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL497444 | 0.90 | GSK3B (0.71) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13722127 | 0.90 | GSK3B (0.84) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13721953 | 0.90 | GSK3B (0.84) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL4027349 | 0.90 | GSK3B (0.84) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL497065 | 0.89 | GSK3B (0.72) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13722266 | 0.89 | GSK3B (0.83) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |