SCHEMBL13722366

SCHEMBL13722366

Cn1c(C(=O)NC2CCCC[C@@H]2O)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.79

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 19/20 0.79
CNR2 P34972 1/20 0.58
OPRL1 P41146 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4076169 1.00 CNR1 (0.79) CNR1CNR2OPRL1
SCHEMBL4077605 1.00 CNR1 (0.79) CNR1CNR2OPRL1
SCHEMBL13722187 1.00 CNR1 (0.79) CNR1CNR2OPRL1
SCHEMBL4080151 0.88 CNR1 (1.00) CNR1OPRL1
SCHEMBL13722544 0.88 CNR1 (0.75) CNR1OPRL1
SCHEMBL4085592 0.88 CNR1 (0.75) CNR1OPRL1
SCHEMBL13749359 0.88 CNR1 (0.75) CNR1OPRL1
SCHEMBL4076138 0.88 CNR1 (0.75) CNR1OPRL1
SCHEMBL13749041 0.88 CNR1 (0.75) CNR1OPRL1
SCHEMBL13722800 0.88 CNR1 (0.75) CNR1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572785-B2 Substituted imidazoles as cannabinoid receptor modulators MERCK & CO., INC. (US) 2009-08-11 US disclosed