Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13722124 | 0.91 | GSK3B (0.57) | GSK3BADORA2BADORA2AADORA1 | |
| SCHEMBL13910324 | 0.89 | GSK3B (0.73) | GSK3B | |
| SCHEMBL13722101 | 0.87 | GSK3B (0.70) | GSK3B | |
| SCHEMBL13721909 | 0.87 | GSK3B (0.70) | GSK3B | |
| SCHEMBL13721713 | 0.85 | GSK3B (0.53) | GSK3BADORA2BADORA2AADORA1 | |
| SCHEMBL13721944 | 0.85 | GSK3B (0.54) | GSK3BADORA2BADORA2AADORA1 | |
| SCHEMBL4031690 | 0.85 | GSK3B (0.75) | GSK3B | |
| SCHEMBL13721914 | 0.85 | GSK3B (0.57) | GSK3B | |
| SCHEMBL13722148 | 0.85 | GSK3B (0.68) | GSK3B | |
| SCHEMBL13721903 | 0.85 | GSK3B (0.69) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |