Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.82 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.69 |
| ▸ | GSK3A | P49840 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13722055 | 1.00 | GSK3B (0.82) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL4026600 | 1.00 | GSK3B (0.82) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13722661 | 0.90 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL4028687 | 0.90 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL4027426 | 0.90 | GSK3B (0.83) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL4026204 | 0.90 | GSK3B (0.83) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13721973 | 0.90 | GSK3B (0.83) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL4028695 | 0.90 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13722252 | 0.89 | GSK3B (0.82) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL4024765 | 0.89 | GSK3B (0.82) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-7572793-B2 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |