Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13147604 | 1.00 | MC4R (0.52) | MC4RKCNH2HSD17B10 | |
| SCHEMBL13146934 | 0.93 | MC4R (0.51) | MC4RKCNH2HSD17B10 | |
| SCHEMBL13146951 | 0.92 | MC4R (0.49) | MC4RKCNH2 | |
| SCHEMBL13146930 | 0.90 | MC4R (0.47) | MC4RKCNH2 | |
| SCHEMBL13146916 | 0.89 | MC4R (0.63) | MC4RKCNH2 | |
| SCHEMBL13147603 | 0.89 | MC4R (0.63) | MC4RKCNH2 | |
| SCHEMBL3823723 | 0.88 | MC4R (0.58) | MC4RHSD17B10 | |
| SCHEMBL3093393 | 0.85 | MC4R (0.56) | MC4RHSD17B10 | |
| SCHEMBL3093389 | 0.85 | MC4R (0.56) | MC4RHSD17B10 | |
| SCHEMBL3096150 | 0.85 | MC4R (0.66) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7365070-B2 | Modulators of melanocortin receptor | ORE PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365070-B2 | Modulators of melanocortin receptor | ORE PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |