Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 10/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3089933 | 0.79 | MC4R (0.69) | MC4R | |
| SCHEMBL13180228 | 0.78 | MC4R (0.48) | MC4R | |
| SCHEMBL13147074 | 0.78 | MC4R (0.58) | MC4RKCNH2 | |
| SCHEMBL13147075 | 0.77 | MC4R (0.59) | MC4RKCNH2 | |
| SCHEMBL13723344 | 0.77 | MC4R (0.49) | MC4R | |
| SCHEMBL13147102 | 0.76 | MC4R (0.51) | MC4RKCNH2ALDH1A1LMNA | |
| SCHEMBL13147315 | 0.73 | MC4R (0.54) | MC4RKCNH2 | |
| SCHEMBL13724355 | 0.73 | MC4R (0.48) | MC4R | |
| SCHEMBL13147308 | 0.73 | MC4R (0.49) | MC4RKCNH2 | |
| SCHEMBL13147155 | 0.72 | MC4R (0.58) | MC4RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |