Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 14/20 | 0.62 |
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13146946 | 0.92 | MC4R (0.73) | MC4R | |
| SCHEMBL13724664 | 0.83 | MC4R (0.64) | MC4R | |
| SCHEMBL13146941 | 0.83 | MC4R (0.77) | MC4R | |
| SCHEMBL13146927 | 0.83 | MC4R (0.77) | MC4R | |
| SCHEMBL3080662 | 0.77 | MC4R (0.84) | MC4R | |
| SCHEMBL3080663 | 0.77 | MC4R (0.84) | MC4R | |
| SCHEMBL3822981 | 0.77 | MC4R (1.00) | MC4R | |
| SCHEMBL3077963 | 0.76 | MC4R (0.88) | MC4R | |
| SCHEMBL3077948 | 0.76 | MC4R (0.88) | MC4R | |
| SCHEMBL13146977 | 0.75 | MC4R (0.65) | MC4RKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |