Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13725566 | 1.00 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL4117544 | 1.00 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL3022890 | 0.91 | MEN1 (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9294560 | 0.91 | MEN1 (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9295206 | 0.91 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL16685006 | 0.91 | TSHR (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9470760 | 0.86 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL28203082 | 0.86 | MEN1 (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL28106829 | 0.86 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9469818 | 0.86 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150866-A1 | PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF | INDUSTRIAL RESEARCH LIMITED (NZ) | 2012-11-08 | — | — | WO | disclosed |