Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590288 | 0.89 | F10 (0.62) | F10POLBKLKB1MEN1KMT2A | |
| SCHEMBL8280052 | 0.87 | POLB (0.58) | F10POLBKLKB1MEN1KMT2A | |
| SCHEMBL3835351 | 0.87 | F10 (0.58) | F10POLBKLKB1MEN1KMT2A | |
| SCHEMBL3834358 | 0.86 | F10 (0.62) | F10POLBKLKB1MEN1KMT2A | |
| SCHEMBL3830778 | 0.85 | F10 (0.59) | F10POLBKLKB1MEN1KMT2A | |
| SCHEMBL8272842 | 0.85 | F10 (0.59) | F10POLBKLKB1MEN1KMT2A | |
| SCHEMBL8282294 | 0.84 | F10 (0.55) | F10POLBKLKB1MEN1KMT2A | |
| SCHEMBL3588150 | 0.84 | F10 (0.62) | F10POLBKLKB1MEN1KMT2A | |
| SCHEMBL3832105 | 0.83 | F10 (0.59) | F10POLBKLKB1MAPT | |
| SCHEMBL8273027 | 0.83 | F10 (0.59) | F10POLBKLKB1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085391-A2 | Inhibitors of factor XA and other serine proteases involved in the coagulation cascade | Warner-Lambert Company LLC (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1671949-B1 | Substituted Pyridinylamines | WARNER LAMBERT CO (US) | 2008-07-23 | — | — | EP | disclosed |