Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14143346 | 0.97 | F10 (0.48) | F10TYK2CFDKLKB1 | |
| SCHEMBL13725896 | 0.82 | F10 (0.55) | F10CFD | |
| SCHEMBL3828769 | 0.81 | F10 (0.51) | F10TYK2 | |
| SCHEMBL3829968 | 0.81 | F10 (0.69) | F10KLKB1F2 | |
| SCHEMBL3832154 | 0.81 | F10 (0.70) | F10KLKB1F2 | |
| SCHEMBL3836109 | 0.81 | F10 (0.70) | F10KLKB1F2 | |
| SCHEMBL3835819 | 0.78 | F10 (0.55) | F10KLKB1 | |
| SCHEMBL3828327 | 0.78 | F10 (0.71) | F10KLKB1F2 | |
| SCHEMBL3828777 | 0.78 | F10 (0.48) | F10TYK2 | |
| SCHEMBL3833444 | 0.78 | F10 (0.56) | F10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085391-A2 | Inhibitors of factor XA and other serine proteases involved in the coagulation cascade | Warner-Lambert Company LLC (US) | 2009-08-05 | — | — | EP | disclosed |