Edetic Acid

Edetic Acid

SCHEMBL1373

O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 1.00
EYA2 O00167 1/20 1.00
APP P05067 1/20 1.00
ACE P12821 1/20 1.00
BLM P54132 2/20 0.93
PMP22 Q01453 2/20 0.93
TSHR P16473 2/20 0.93
KDM4E B2RXH2 2/20 0.93
ALOX15 P16050 2/20 0.93
LMNA P02545 1/20 0.93
CHRM2 P08172 1/20 0.93
ADRA2A P08913 1/20 0.93
DRD1 P21728 1/20 0.93
SLC6A2 P23975 1/20 0.93
SLC6A4 P31645 1/20 0.93
CYP2C19 P33261 1/20 0.93
ADRA1A P35348 1/20 0.93
DRD3 P35462 1/20 0.93
SLC6A3 Q01959 1/20 0.93
HRH3 Q9Y5N1 1/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edetic Acid SCHEMBL15136 1.00 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL16714076 1.00 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL8607480 1.00 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL8624198 1.00 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL3035039 1.00 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL1396918 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL191925 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL2115351 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL2010607 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL22534098 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 1332471 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372755-B1 None US claimed
US-9974844-B2 Cancer vaccine compositions and methods of using the same THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2018-05-22 US claimed
US-20180135128-A1 METHODS FOR DETECTING CYSTIC FIBROSIS MUTATIONS USING MITRA TIP EXTRACTION QUEST DIAGNOSTICS INVESTMENTS LLC (US) 2018-05-17 US claimed
US-20180133142-A1 COSMETIC PREPARATION WITH IMPROVED VISCOSITY FOR TREATING KERATIN FIBERS, A PROCESS FOR INCREASING THE VISCOSITY OF A COSMETIC PREPARATION, USE OF VISCOSITY MODIFYING INGREDIENTS, AND A METHOD OF TREATING KERATIN FIBERS Natura Cosméticos S.A. (BR) 2018-05-17 US claimed
US-20180135009-A1 Lgr5+ SOMATIC STEM CELLS STEMBIOS TECH INC (US) 2018-05-17 US claimed
US-20180134634-A1 Methods and Systems for Measuring Plasma Renin Activity LABORATORY CORPORATION OF AMERICA HOLDINGS 2018-05-17 US claimed
US-20180134632-A1 EXTRACTION OF AMINO ACIDS AND PHOSPHORUS FROM BIOLOGICAL MATERIALS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2018-05-17 US claimed
US-20180133706-A1 CATALYST BASED ON y-KETOVALERIC ACID AND USE THEREOF IN A HYDROTREATMENT AND/OR HYDROCRACKING PROCESS IFP Energies Nouvelles (FR) 2018-05-17 US claimed
WO-2018089540-A1 STABILIZED FORMULATIONS OF LIPID NANOPARTICLES MODERNATX, INC. (US) 2018-05-17 WO claimed
US-20180135135-A1 METHODS FOR DETECTING DNA MUTATIONS USING MITRA TIP EXTRACTION QUEST DIAGNOSTICS INVESTMENTS LLC (US) 2018-05-17 US claimed
US-3966502-A Zirconium rinse for phosphate coated metal surfaces AMCHEM PRODUCTS, INC. (US) 1976-06-29 US claimed
US-3964832-A Gel composition and adhesive stick THE CARTER'S INK COMPANY (US) 1976-06-22 US claimed
US-3963578-A ASPARTATE, ETHYLENEDIAMINETETRAACETIC ACID, AMMONIUM SULFATE, SODIUM PHOSPHATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-15 US claimed
US-3961038-A Process for the manufacture of injectable preparations of Tc99m and/or In113m and apparatus for carrying out the process SOLCO BASEL AG (CH) 1976-06-01 US claimed
US-3954967-A Method of producing microcolloidal aqueous emulsions of unsaturated organic insecticidal compounds VANGUARD CHEMICAL COMPANY, INC. (US) 1976-05-04 US claimed
US-3951917-A SALT OF ETHYLENEDIAMINE TETRAACETIC ACID AND AN ANTISOLVENT GENERAL ELECTRIC COMPANY (US) 1976-04-20 US claimed
US-3948833-A Compositions for rigid asbestos - reinforced polyvinyl chloride CENTRE FOR INDUSTRIAL RESEARCH (CIR) LTD. (IL) 1976-04-06 US claimed
US-3945824-A HETEROCYCLIC COMPOUND, PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JA) 1976-03-23 US claimed
US-3932657-A Liposome encapsulation of chelating agents THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES ENERGY RESEARCH AND DEVELOPMENT ADMINISTRATION (US) 1976-01-13 US claimed
US-3930845-A PRODUCING HIGH PURITY GOLD POWDER ANGLO AMERICAN CORPORATION OF SOUTH AFRICA (ZA) 1976-01-06 US claimed