⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pivalate SCHEMBL27622088 | 0.87 | EGLN1 (0.35) | — | |
| SCHEMBL190462 | 0.79 | — | — | |
| SCHEMBL7422071 | 0.79 | — | — | |
| SCHEMBL190463 | 0.79 | — | — | |
| SCHEMBL716313 | 0.78 | GLI1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL204916 | 0.77 | EGLN1 (0.59) | — | |
| SCHEMBL13804343 | 0.77 | — | — | |
| Bromide SCHEMBL7324484 | 0.77 | EGLN1 (0.59) | — | |
| SCHEMBL30530660 | 0.72 | EGLN1 (0.35) | — | |
| SCHEMBL13979483 | 0.72 | EGLN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084935-A | Imidazolidinone compound as well as preparation method and application thereof | 贝达药业股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| EP-3472149-B1 | HETEROCYCLIC PROLINAMIDE DERIVATIVES | Orion Ophthalmology LLC (US) | 2023-08-30 | — | — | EP | claimed |
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| CN-118084935-A | Imidazolidinone compound as well as preparation method and application thereof | 贝达药业股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114599655-B | Imidazolidinone compound as well as preparation method and application thereof | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117377496-A | Compounds for degrading alpha-synuclein aggregates and uses thereof | 新旭生技股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-114599655-A | Imidazolidinone compound and preparation method and application thereof | 贝达药业股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| US-8791102-B2 | Acetanilide sphingosine-1-phosphate receptor antagonists | EXELIXIS, INC. (US) | 2014-07-29 | — | — | US | disclosed |
| US-20110288076-A1 | Sphingosine-1-Phosphate Receptor Antagonists | EXELIXIS, INC. (US) | 2011-11-24 | — | — | US | disclosed |
| CN-102256944-A | Sphingosine-1-phosphate receptor antagonists | EXELIXIS INC | 2011-11-23 | — | — | CN | disclosed |
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010045580-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | EXELIXIS, INC. (US) | 2010-04-22 | — | — | WO | disclosed |