Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 4/20 | 0.92 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL19856402 | 1.00 | SLC22A1 (0.92) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL27702955 | 1.00 | SLC22A1 (0.92) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL37663 | 1.00 | SLC22A1 (0.92) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL8679645 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL21525926 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL25332097 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL11349437 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL28484893 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL4299822 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL29043619 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102008898-B | Method for preparing positive charge microfiltration membrane | AMERICAN MEMBRANE NANTONG CO LTD | 2013-06-05 | — | — | CN | claimed |
| CN-102008898-A | Method for preparing positive charge microfiltration membrane | AMERICAN MEMBRANE NANTONG CO LTD | 2011-04-13 | — | — | CN | claimed |
| CN-1107833-A | Process for preparing diaryl carbonates | BAYER AG (DE) | 1995-09-06 | — | — | CN | claimed |
| WO-2024015589-A1 | PERSONAL CARE DEVICES AND COSMETIC COMPOSITIONS | PATHAK HOLDINGS LLC (US) | 2024-01-18 | — | — | WO | disclosed |
| CN-111423587-B | Thermosetting silicon-containing compound, composition for forming silicon-containing film, and method for forming pattern | 信越化学工业株式会社 | 2023-01-31 | — | — | CN | disclosed |
| US-20220118416-A1 | CROSSLINKED MULTILAYERED MATERIAL COMPOSITIONS, METHODS FOR THEIR PREPARATION AND APPLICATIONS THEREOF | PATHAK HOLDINGS LLC | 2022-04-21 | — | — | US | disclosed |
| CN-107540670-B | Preparation method of 1- (3-chloropyrazolo [1,5a ] -4,5,6, 7-tetrahydropyridine-2-yl) -5-methylamine pyrazole-4-carbonitrile | 湖北相和精密化学有限公司 | 2021-08-13 | — | — | CN | disclosed |
| EP-2864840-B1 | COATED PHOTOCONDUCTORS | HEWLETT PACKARD DEVELOPMENT CO (US) | 2018-10-03 | — | — | EP | disclosed |
| US-20180098542-A1 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| US-9933715-B2 | Coated photoconductors | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2018-04-03 | — | — | US | disclosed |
| CN-107674826-A | A kind of liquid bacterial culture device | 陕西众兴高科生物科技有限公司 | 2018-02-09 | — | — | CN | disclosed |
| CN-1054836-C | Process for preparing diaryl carbonates | BAYER AG (DE) | 2000-07-26 | — | — | CN | disclosed |
| CN-1183771-A | Process for preparing racemic and enantiomeric 1- (pyridyl) -2-cyclohexylethylamine | BOEHRINGER INGELHEIM PHARMA (US) | 1998-06-03 | — | — | CN | disclosed |
| CN-1128763-A | Oxazoloquinolinone derivatives, their preparation and their therapeutic use | SYNTHELABO (FR) | 1996-08-14 | — | — | CN | disclosed |
| CN-1107833-A | Process for preparing diaryl carbonates | BAYER AG (DE) | 1995-09-06 | — | — | CN | disclosed |
| US-4861787-A | Nematicidal compositions | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0263066-A2 | 2-Mercapto-oxadiazole and -thiadiazole derivatives, process for their preparation and nematicides containing them | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |
| EP-0128465-B1 | PROCESS FOR PRODUCING BROMINATED ACENAPHTHYLENE CONDENSATES | TOSOH CORPORATION (JP) | 1986-08-27 | — | — | EP | disclosed |
| US-4333809-A | Cross-linkable polycarbonate elastomers, a process for their preparation and use for packaging medicines | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| US-4145484-A | LITHIUM, BROMINE, TETRABUTYLAMMONIUM BROMIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1979-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180098542-A1 | METHODS OF PEST CONTROL IN SOYBEAN | BTF3, BRS3, CCNB3 | SLC22A1 2452/4885SLC22A2 2414/4885TSHR 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.