Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.84 |
| ▸ | HDAC2 | Q92769 | 20/20 | 0.84 |
| ▸ | HDAC3 | O15379 | 17/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13833480 | 0.91 | HDAC1 (1.00) | HDAC1HDAC2HDAC3 | |
| SCHEMBL13833484 | 0.89 | HDAC1 (1.00) | HDAC1HDAC2HDAC3 | |
| SCHEMBL13833407 | 0.88 | HDAC1 (0.80) | HDAC1HDAC2HDAC3 | |
| SCHEMBL13833343 | 0.88 | HDAC1 (1.00) | HDAC1HDAC2HDAC3 | |
| SCHEMBL13833340 | 0.86 | HDAC1 (1.00) | HDAC1HDAC2HDAC3 | |
| SCHEMBL13833336 | 0.86 | HDAC1 (1.00) | HDAC1HDAC2HDAC3 | |
| SCHEMBL15522856 | 0.85 | HDAC1 (0.62) | HDAC1HDAC2HDAC3 | |
| SCHEMBL15522858 | 0.85 | HDAC1 (0.62) | HDAC1HDAC2HDAC3 | |
| SCHEMBL13833408 | 0.85 | HDAC2 (1.00) | HDAC1HDAC2HDAC3 | |
| SCHEMBL13833349 | 0.85 | HDAC1 (1.00) | HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2701699-A1 | INHIBITORS OF HISTONE DEACETYLASE | The Broad Institute, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012149540-A1 | INHIBITORS OF HISTONE DEACETYLASE | THE BROAD INSTITUTE INC (US) | 2012-11-01 | — | — | WO | disclosed |