Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 14/20 | 0.91 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248176 | 0.95 | DHODH (1.00) | DHODHNPSR1NR4A1NR4A2PARP1 | |
| SCHEMBL3914512 | 0.90 | DHODH (0.89) | DHODHNPSR1NR4A2PARP1PARP15 | |
| SCHEMBL517712 | 0.88 | DHODH (0.85) | DHODHNPSR1NR4A1NR4A2PARP1 | |
| SCHEMBL253516 | 0.83 | DHODH (1.00) | DHODHNPSR1NR4A2SGMS2RAB9A | |
| SCHEMBL3924492 | 0.81 | DHODH (0.74) | DHODHNPSR1NR4A2PARP1PARP15 | |
| SCHEMBL247329 | 0.81 | DHODH (1.00) | DHODHNPSR1PARP1PARP15PARP10 | |
| SCHEMBL290914 | 0.81 | DHODH (0.89) | DHODHNPSR1NR4A1NR4A2PARP1 | |
| SCHEMBL3915847 | 0.81 | DHODH (0.78) | DHODHNPSR1NR4A1NR4A2NPC1 | |
| SCHEMBL18418380 | 0.81 | DHODH (0.73) | DHODHNPSR1NR4A2PARP1PARP15 | |
| SCHEMBL3926083 | 0.79 | DHODH (0.78) | DHODHNPSR1PARP1PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2093214-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2009-08-26 | — | — | EP | disclosed |