Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 18/20 | 0.72 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.56 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926145 | 0.93 | DHODH (0.82) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL252179 | 0.88 | DHODH (0.83) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL503290 | 0.84 | DHODH (1.00) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL3924727 | 0.84 | DHODH (0.84) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL19417217 | 0.82 | DHODH (0.70) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL502990 | 0.82 | DHODH (0.77) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL3924601 | 0.81 | DHODH (0.78) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL502883 | 0.80 | DHODH (1.00) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL253220 | 0.80 | DHODH (0.77) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL502900 | 0.80 | DHODH (0.83) | DHODHNR4A2JMJD7NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2093214-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2009-08-26 | — | — | EP | disclosed |