Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653420 | 0.82 | BRD4 (0.60) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL13090519 | 0.78 | MAPT (0.42) | BRD4LMNAALDH1A1MAPTGAA | |
| SCHEMBL1990722 | 0.78 | BRD4 (0.45) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL29715369 | 0.77 | BRD4 (0.51) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL4063807 | 0.77 | BRD4 (0.51) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL23099736 | 0.77 | BRD4 (0.51) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL1323798 | 0.76 | POLB (0.46) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL560921 | 0.76 | POLB (0.46) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL498176 | 0.76 | POLB (0.46) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL7350858 | 0.76 | BRD4 (0.50) | BRD4OPRM1OPRD1OPRK1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098901-A1 | 3,8-DIAMINOTETRAHYDROQUINOLINE DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2009-08-13 | — | — | WO | disclosed |