Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.82 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008890 | 0.90 | KMT2A (1.00) | KMT2AFFAR1MEN1MAPTPKM | |
| SCHEMBL12008977 | 0.90 | KMT2A (1.00) | KMT2AFFAR1MEN1MAPTPKM | |
| SCHEMBL12008872 | 0.89 | KMT2A (0.98) | KMT2AFFAR1MEN1MAPTPKM | |
| SCHEMBL18539173 | 0.85 | KMT2A (0.86) | KMT2AFFAR1MEN1MAPTPKM | |
| SCHEMBL12008990 | 0.85 | KMT2A (0.86) | KMT2AFFAR1MEN1MAPTPKM | |
| SCHEMBL12008887 | 0.82 | KMT2A (0.84) | KMT2AFFAR1MEN1MAPTALDH1A1 | |
| SCHEMBL12008950 | 0.82 | FFAR1 (0.86) | KMT2AFFAR1MEN1MAPTPKM | |
| SCHEMBL18545589 | 0.81 | FFAR1 (0.73) | KMT2AFFAR1MEN1MAPTPKM | |
| SCHEMBL12008871 | 0.80 | KMT2A (0.81) | KMT2AFFAR1MEN1MAPTPKM | |
| SCHEMBL12008952 | 0.79 | FFAR1 (0.70) | KMT2AFFAR1MEN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097113-A2 | OXAZOLE AND THIAZOLE COMPOUNDS AS B-CATENIN MODULATORS AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2009-08-06 | — | — | WO | disclosed |