Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.41 |
| ▸ | CETP | P11597 | 5/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153591 | 0.93 | PTGDR2 (0.42) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL151825 | 0.91 | PTGDR2 (0.42) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL13746076 | 0.90 | PTGDR2 (0.44) | PTGDR2CETPTBXA2RPTGDRAKR1C3 | |
| SCHEMBL136568 | 0.89 | CETP (0.40) | PTGDR2CETPTBXA2RPTGDRAKR1C3 | |
| SCHEMBL154195 | 0.82 | AKR1C3 (0.47) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL153528 | 0.81 | PTGDR2 (0.52) | PTGDR2 | |
| SCHEMBL152863 | 0.81 | CETP (0.57) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL151690 | 0.80 | AKR1C3 (0.45) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL152595 | 0.79 | PTGDR2 (0.50) | PTGDR2 | |
| SCHEMBL137674 | 0.79 | CTSA (0.37) | AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099902-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |