Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1208137 | 0.84 | AR (0.47) | ARCNR1TSHRNOTUM | |
| SCHEMBL14295900 | 0.80 | AR (0.47) | ARCNR1 | |
| SCHEMBL14300669 | 0.80 | AR (0.47) | ARCNR1 | |
| SCHEMBL1209014 | 0.78 | AR (0.46) | ARCNR1 | |
| SCHEMBL3527116 | 0.73 | AR (0.54) | ARCNR1HDAC1 | |
| SCHEMBL1974598 | 0.73 | CNR1 (0.55) | ARCNR1HDAC1 | |
| SCHEMBL8002084 | 0.72 | CNR1 (0.58) | ARCNR1HDAC1 | |
| SCHEMBL1973176 | 0.72 | AR (0.58) | ARCNR1 | |
| SCHEMBL2216155 | 0.72 | AR (0.52) | ARCNR1 | |
| Hydrochloric Acid SCHEMBL6522010 | 0.72 | CNR1 (0.57) | ARCNR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098000-A1 | HETEROCYCLICALLY-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |