Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.84 |
| ▸ | CETP | P11597 | 2/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.64 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | PTGIR | P43119 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138779 | 0.92 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL253825 | 0.91 | PTGDR2 (0.85) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL150210 | 0.91 | PTGDR2 (0.85) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL29402580 | 0.91 | PTGDR2 (0.85) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL150186 | 0.90 | PTGDR2 (0.78) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL154283 | 0.89 | PTGDR2 (0.82) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL142820 | 0.88 | PTGDR2 (0.93) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL136971 | 0.88 | PTGDR2 (0.93) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL150112 | 0.86 | PTGDR2 (0.77) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL155446 | 0.86 | PTGDR2 (0.71) | PTGDR2CETPTBXA2RPTGDRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099902-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |