Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008894 | 0.91 | FFAR1 (0.71) | FFAR1MEN1KMT2AGPR55NPC1 | |
| SCHEMBL12008966 | 0.90 | FFAR1 (0.70) | FFAR1MEN1KMT2AGPR55NPC1 | |
| SCHEMBL12008971 | 0.85 | KMT2A (0.65) | FFAR1MEN1KMT2ANPC1MAPT | |
| SCHEMBL12008925 | 0.84 | POLB (0.73) | FFAR1MEN1KMT2AGPR55NPC1 | |
| SCHEMBL12008980 | 0.84 | KMT2A (0.66) | FFAR1MEN1KMT2ANPC1MAPT | |
| SCHEMBL12008920 | 0.83 | FFAR1 (0.64) | FFAR1MEN1KMT2AGPR55NPC1 | |
| SCHEMBL18539174 | 0.81 | NPC1 (0.57) | FFAR1MEN1KMT2AGPR55NPC1 | |
| SCHEMBL12006896 | 0.80 | FFAR1 (1.00) | FFAR1MEN1KMT2AGPR55NPC1 | |
| SCHEMBL12008850 | 0.79 | MEN1 (0.68) | FFAR1MEN1KMT2AGPR55NPC1 | |
| SCHEMBL12008926 | 0.79 | KMT2A (0.75) | FFAR1MEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097113-A2 | OXAZOLE AND THIAZOLE COMPOUNDS AS B-CATENIN MODULATORS AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2009-08-06 | — | — | WO | disclosed |