Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 16/20 | 0.51 |
| ▸ | BIRC2 | Q13490 | 14/20 | 0.50 |
| ▸ | BIRC3 | Q13489 | 10/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13747240 | 0.93 | XIAP (0.48) | XIAPBIRC2BIRC3 | |
| SCHEMBL13164630 | 0.92 | XIAP (0.58) | XIAPBIRC2BIRC3 | |
| SCHEMBL13746451 | 0.92 | XIAP (0.53) | XIAPBIRC2BIRC3 | |
| SCHEMBL13747130 | 0.90 | XIAP (0.56) | XIAPBIRC2BIRC3 | |
| SCHEMBL13746517 | 0.89 | BIRC2 (0.50) | XIAPBIRC2BIRC3 | |
| SCHEMBL13746561 | 0.88 | BIRC2 (0.46) | XIAPBIRC2BIRC3 | |
| SCHEMBL13872851 | 0.88 | XIAP (0.53) | XIAPBIRC2BIRC3 | |
| SCHEMBL13747108 | 0.88 | BIRC2 (0.48) | XIAPBIRC2BIRC3 | |
| SCHEMBL13872872 | 0.86 | XIAP (0.49) | XIAPBIRC2BIRC3 | |
| SCHEMBL13164633 | 0.86 | XIAP (0.55) | XIAPBIRC2BIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579320-B2 | IAP BIR domain binding compounds | AEGERA THERAPEUTICS, INC. | 2009-08-25 | — | — | US | disclosed |
| US-7579320-B2 | IAP BIR domain binding compounds | AEGERA THERAPEUTICS, INC. | 2009-08-25 | — | — | US | disclosed |