Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 5/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029839 | 0.86 | SCARB1 (0.67) | SCARB1BCHEACHE | |
| SCHEMBL13747467 | 0.82 | BCHE (0.52) | BCHEACHEALB | |
| SCHEMBL13746604 | 0.69 | SCARB1 (0.62) | SCARB1BCHEACHE | |
| SCHEMBL4200829 | 0.67 | SCARB1 (0.62) | SCARB1 | |
| SCHEMBL1003026 | 0.67 | MCHR1 (0.52) | BCHEACHEALB | |
| SCHEMBL10155031 | 0.66 | BCHE (0.66) | BCHEACHEALB | |
| SCHEMBL10155029 | 0.65 | BCHE (0.61) | BCHEACHEALB | |
| SCHEMBL19559319 | 0.64 | BACE1 (0.52) | — | |
| SCHEMBL798107 | 0.63 | RIPK3 (0.54) | BCHEACHEALB | |
| SCHEMBL10155030 | 0.61 | BCHE (0.60) | BCHEACHEALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |