⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26386577 | 1.00 | — | — | |
| SCHEMBL26386601 | 1.00 | — | — | |
| SCHEMBL26386620 | 1.00 | — | — | |
| SCHEMBL13746860 | 1.00 | — | — | |
| SCHEMBL26386625 | 1.00 | — | — | |
| SCHEMBL20438773 | 1.00 | — | — | |
| SCHEMBL26386608 | 0.86 | — | — | |
| SCHEMBL16884371 | 0.86 | — | — | |
| SCHEMBL2065409 | 0.83 | — | — | |
| SCHEMBL12163215 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244802-A1 | Protein Demethylases Comprising a JMJC Domain | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2016-08-25 | — | — | US | disclosed |
| US-20090203057-A1 | PROTEIN DEMETHYLASES COMPRISING A JMJC DOMAIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-08-13 | — | — | US | disclosed |