Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.57 |
| ▸ | CCR5 | P51681 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13747830 | 0.94 | ACKR3 (0.56) | ACKR3CCR5NPC1MCHR1MEN1 | |
| SCHEMBL13746970 | 0.88 | ACKR3 (0.55) | ACKR3CCR5NPC1MCHR1MEN1 | |
| SCHEMBL13747197 | 0.86 | ACKR3 (0.50) | ACKR3CCR5NPC1MCHR1MEN1 | |
| SCHEMBL13616320 | 0.82 | ACKR3 (0.57) | ACKR3CCR5NPC1MEN1KMT2A | |
| SCHEMBL3431124 | 0.81 | GRIN1 (0.60) | ACKR3CCR5NPC1MEN1KMT2A | |
| SCHEMBL3431127 | 0.81 | GRIN1 (0.60) | ACKR3CCR5NPC1MEN1KMT2A | |
| SCHEMBL13746729 | 0.80 | ACKR3 (0.49) | ACKR3CCR5NPC1MEN1KMT2A | |
| SCHEMBL3428172 | 0.80 | ACKR3 (0.49) | ACKR3CCR5NPC1MEN1KMT2A | |
| SCHEMBL3428171 | 0.80 | ACKR3 (0.49) | ACKR3CCR5NPC1MEN1KMT2A | |
| SCHEMBL13630619 | 0.80 | MEN1 (0.45) | NPC1MEN1KMT2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097695-A1 | ARYLMETHYLIDENE HETEROCYCLES AS NOVEL ANALGESICS | CHLORION PHARMA, INC. (CA) | 2009-08-13 | — | — | WO | disclosed |