Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 16/20 | 0.55 |
| ▸ | BIRC2 | Q13490 | 11/20 | 0.55 |
| ▸ | BIRC3 | Q13489 | 10/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13164553 | 1.00 | XIAP (0.55) | XIAPBIRC2BIRC3 | |
| SCHEMBL13164551 | 0.87 | ELANE (0.52) | XIAPBIRC2BIRC3 | |
| SCHEMBL13184540 | 0.86 | XIAP (0.53) | XIAPBIRC2BIRC3 | |
| SCHEMBL13164683 | 0.85 | XIAP (0.52) | XIAPBIRC2BIRC3 | |
| SCHEMBL13164552 | 0.85 | XIAP (0.43) | XIAPBIRC2BIRC3 | |
| SCHEMBL13746451 | 0.84 | XIAP (0.53) | XIAPBIRC2BIRC3 | |
| SCHEMBL13164550 | 0.84 | MC4R (0.46) | XIAPBIRC2BIRC3 | |
| SCHEMBL13754047 | 0.83 | XIAP (0.60) | XIAPBIRC2BIRC3 | |
| SCHEMBL13164535 | 0.83 | XIAP (0.60) | XIAPBIRC2BIRC3 | |
| SCHEMBL13746641 | 0.81 | XIAP (0.58) | XIAPBIRC2BIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579320-B2 | IAP BIR domain binding compounds | AEGERA THERAPEUTICS, INC. | 2009-08-25 | — | — | US | disclosed |
| US-7579320-B2 | IAP BIR domain binding compounds | AEGERA THERAPEUTICS, INC. | 2009-08-25 | — | — | US | disclosed |
| US-20080069812-A1 | Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents | AEGERA THERAPEUTICS, INC. (CA) | 2008-03-20 | — | — | US | disclosed |
| US-20080069812-A1 | Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents | AEGERA THERAPEUTICS, INC. (CA) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080069812-A1 | Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents | BIRC5, XIAP, BIRC2 | XIAP 2/4885BIRC2 3/4885BIRC3 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.