Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746931 | 0.94 | NPC1 (0.40) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616084 | 0.93 | NPC1 (0.42) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616095 | 0.92 | NPC1 (0.41) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616083 | 0.87 | NPC1 (0.42) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13747080 | 0.86 | MEN1 (0.40) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616096 | 0.86 | NPC1 (0.40) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616105 | 0.86 | NPC1 (0.38) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616068 | 0.85 | MEN1 (0.43) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616098 | 0.85 | MEN1 (0.38) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616073 | 0.84 | MEN1 (0.41) | NPC1MEN1KMT2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097695-A1 | ARYLMETHYLIDENE HETEROCYCLES AS NOVEL ANALGESICS | CHLORION PHARMA, INC. (CA) | 2009-08-13 | — | — | WO | disclosed |